Benadryl DR Syrup is an antitussive medicine. It is used for the treatment of dry cough. It helps by reducing the activity of the cough center in the brain. Benadryl DR Syrup can be taken with or without food. Take it whenever necessary or as prescribed by the doctor. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Inform your doctor if symptoms do not get improved. The most common side effects of this medicine include sleepiness, dizziness, confusion, and nausea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Generally, it is advised to drink plenty of fluids while on treatment with this medicine. To overcome dizziness, avoid driving or attention-seeking activities. Before taking this medicine, let your doctor know if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.